[A pharmacological analysis of the GABA-ergic system of the primordial hippocampus in the frog Rana temporaria].

Article date: 1991/1/1

PubMed ID: 1661181

Journal name: Nauchnye doklady vysshei shkoly. Biologicheskie nauki (ISSN: 0470-4606)


The data on evoked potentials (EP) in the frog primordial hippocampus during the surface application of gamma-aminobutyric acid (GABA), beta-alanine and aminooxyacetic acid in the region of EP recording are presented. These results in the aggregate with the earlier described effects of picrotoxin, bicuculline, muscimol, baclofen (on EP) and GABA (on intracellular potentials) permit to suggest the presence of GABA-ergic inhibitory system and two types of GABA receptors in the frog primordial hippocampus.

Author List: Trepakov V V, Saakian S A

Publication Types: English Abstract; Journal Article

Substances mentioned in the article: Receptors, GABA-A;

Mesh terms: Animals; Dose-Response Relationship, Drug; Evoked Potentials/drug effects; Hippocampus/drug effects; Neural Inhibition/drug effects; Rana temporaria; Receptors, GABA-A/drug effects; Time Factors;

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