Article date: 1991/4/1
PubMed ID: 1881982
Journal name: Physiology & behavior (ISSN: 0031-9384)
After bilateral stereotaxic administration of ibotenic acid on the n. basolateralis amygdalae, male adult rats were tested in the light-dark box apparatus to measure the time-course of the acquisition and retention of passive and active avoidance responses. The results show that after the lesions both passive avoidance and active avoidance acquisition were impaired. Passive avoidance responses were retained quite well, while active avoidance responses disappeared quickly. Conditioned freezing was almost completely absent. Thus it appears that the n. basolateralis plays a facilitatory role in all the conditioned responses which were investigated.
Author List: Ambrogi Lorenzini C, Bucherelli C, Giachetti A, Mugnai L, Tassoni G
Publication Types: Journal Article
Substances mentioned in the article: Ibotenic Acid;
Mesh terms: Amygdala/drug effects; Animals; Avoidance Learning/drug effects; Brain Mapping; Conditioning, Classical/drug effects; Electroshock; Fear/drug effects; Ibotenic Acid/pharmacology; Male; Motor Activity/drug effects; Rats; Rats, Inbred Strains; Reaction Time/drug effects;