Article date: 1989/1/1
PubMed ID: 2566989
Journal name: Pharmacological research (ISSN: 1043-6618)
It is now indisputably established that a cohort of neurotransmitters and neuropeptides affect the secretion of anterior pituitary hormones by modulating the functional activity of specific hypophysiotropic regulatory hormones. Some salient aspects of the role of gamma-aminobutyric acid in the control of prolactin secretion and of catecholamines and acetylcholine in the control of growth hormone secretion are reviewed, also underlying some diagnostic and therapeutic applications of the new findings in neuroendocrine disorders.
Author List: Müller E E
Publication Types: Journal Article; Research Support, Non-U.S. Gov't; Review
Substances mentioned in the article: GABA Antagonists; Neurotransmitter Agents; Muscimol; Somatostatin; gamma-Aminobutyric Acid; Prolactin; Growth Hormone-Releasing Hormone;
Mesh terms: Animals; Brain Chemistry; GABA Antagonists; Growth Hormone-Releasing Hormone/secretion; Muscimol/pharmacology; Neurotransmitter Agents/physiology; Pituitary Gland, Anterior/physiology; Prolactin/blood; Rats; Somatostatin/secretion; gamma-Aminobutyric Acid/metabolism;