Article date: 1989/6/1
PubMed ID: 2771205
Journal name: Neuroscience research (ISSN: 0168-0102)
Following creation of a unilateral circumscribed lesion in a portion of a cat substantia nigra pars reticulata by microinfusion of ibotenic acid, circling movements toward the contralateral side of the lesion appeared within 2 days and disappeared a few days later. After recovery, the circling movements reappeared when the cats were decerebrated at the premammillary and precollicular level, suggesting that brain centers rostral to the decerebration participate in compensating the circling movements.
Author List: Udo M, Shimada T, Hirose S, Okamura H, Yamamoto H
Publication Types: Journal Article; Research Support, Non-U.S. Gov't
Substances mentioned in the article: Neurotoxins; Oxazoles; Ibotenic Acid;
Mesh terms: Animals; Cats; Caudate Nucleus/drug effects; Ibotenic Acid/toxicity; Neurotoxins/pharmacology; Oxazoles/toxicity; Stereotyped Behavior/drug effects; Substantia Nigra/drug effects;