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27790 [2018/11/20 14:26] (current)
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 +====== [3H]-dopamine release from the rabbit retina.======
 +
 +** Article date:** 1980/1/1
 +~~META:date created = 1980-01-01~~
 +
 +** PubMed ID: 27790 **
 +
 +** Journal name: Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe'​s archive for clinical and experimental ophthalmology (ISSN: 0065-6100) **
 +
 +** ABSTRACT **
 +
 +[3H]-Dopamine was found to be released from the rabbit retina in vitro by light stimulation,​ by 40 mM K+, and by alpha-MSH (alpha-Melanocyte-Stimulating Hormone) down to about 10(-7) M. The effect of alpha-MSH was dose-dependent. A number of known and putative retinal neurotransmitters and agonists (GABA, muscimol, glutamic acid, kainic acid, glycine, and carbachol, all 10(-4) M) were without significant effect. The results show that it is unlikely that there are excitatory receptors on the retinal dopaminergic neurons to any of the conventional transmitters. Further, alpha-MSH seems of interest as a possible neuroactive retinal substance, which was previously not been suspected.
 +
 +===== ===== 
 +
 +Author List: Bauer B, Ehinger B, Aberg L
 +
 +Publication Types: Journal Article; Research Support, Non-U.S. Gov't
 +
 +Substances mentioned in the article: Neurotransmitter Agents; Tritium; Melanocyte-Stimulating Hormones; Potassium; Dopamine; ​
 +
 +Mesh terms: Animals; Dopamine/​metabolism;​ Dose-Response Relationship,​ Drug; Melanocyte-Stimulating Hormones/​pharmacology;​ Neurotransmitter Agents/​antagonists & inhibitors; Photic Stimulation;​ Potassium/​pharmacology;​ Rabbits; Retina/​metabolism;​ Tritium; ​
 +
 +Citations: ​  - //​[[436145]]//​
 +  - //​[[165691]]//​
 +  - //​[[804181]]//​
 +  - //​[[993828]]//​
 +  - //​[[492319]]//​
 +  - //​[[19605132]]//​
 +  - //​[[4328335]]//​
 +  - //​[[4545829]]//​
 +  - //​[[207745]]//​
 +  - //​[[620345]]//​
 +  - //​[[166508]]//​
 +  - //​[[2921]]//​
 +  - //​[[92476]]//​
 +  - //​[[639856]]//​
 +  - //​[[759200]]//​
 +  - //​[[4325307]]//​
 +  - //​[[27792]]//​
 +  - //​[[620681]]//​
 +  - //​[[439027]]//​
 +  - //​[[5017157]]//​
 +  - //​[[590329]]//​
 +  - //​[[688000]]//​
 +  - //​[[580846]]//​
 +  - //​[[14873430]]//​
 +  - //​[[169480]]//​
 +  - //​[[4399083]]//​
 +  - //​[[639860]]//​
 +  - //​[[366617]]//​
 +  - //​[[597719]]//​
 +  - //​[[4907380]]//​
 +  - //​[[38317]]//​
 +  - //​[[27790]]//​
 +
 +{{tag> Potassium Melanocyte-Stimulating_Hormones Dopamine Tritium Neurotransmitter_Agents }}
 +
 +{{keywords>​ Potassium, Melanocyte-Stimulating Hormones, Dopamine, Tritium, Neurotransmitter Agents}}
 +
  
27790.txt ยท Last modified: 2018/11/20 14:26 (external edit)