GABA binding in bovine adrenal medulla membranes is sensitive to baclofen.

Article date: 1987/1/1

PubMed ID: 2890478

Journal name: Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology (ISSN: 0742-8413)


1. The data summarized in this report reveals the existence of GABA binding in the bovine adrenal medulla membranes. 2. Since this binding was displaced not only by muscimol and bicuculline but also by baclofen, results suggest the possibility that both types of receptors (GABAA and GABAB) could be present in bovine adrenal membranes.

This document is available from: http://directlinks.cc/files/muscimol/2890478.pdf

Author List: Martinez P, Gimenez A, Castro E, Oset-Gasque M J, Cañadas S, González M P

Publication Types: Journal Article; Research Support, Non-U.S. Gov't

Substances mentioned in the article: Receptors, GABA-A; Muscimol; gamma-Aminobutyric Acid; Baclofen; Bicuculline;

Mesh terms: Adrenal Medulla/metabolism; Animals; Baclofen/pharmacology; Bicuculline/pharmacology; Cattle; Cell Membrane/metabolism; Kinetics; Muscimol/pharmacology; Receptors, GABA-A/drug effects; gamma-Aminobutyric Acid/metabolism;

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