3024142

[Active principles of plant origin: a tool for studying membrane receptors].

Article date: 1986/9/25

PubMed ID: 3024142

Journal name: Presse medicale (Paris, France : 1983) (ISSN: 0755-4982)

ABSTRACT

Ever since ancient times, considerable interest has been shown in plants for therapeutic use. Nowadays, however, studies of plant extracts are no longer based on empiricism; they provide great support to fundamental research, especially for a better understanding of the mediator/receptor couples. This applies to the study of cholinergic (atropine, muscarine, etc.), adrenergic (yohimbine, rauwolscine, etc.), dopaminergic (apomorphine, bromocriptine, etc.), purinergic (caffeine, theophylline, etc.), opiate (morphine), GABA (strychnine, muscimol, bicuculline, etc.), cardiac glycosides (gitaloxin, digitoxin) and PAF-acether receptors (ginkgolides from Ginkgo biloba).

Author List: Plat M

Publication Types: English Abstract; Journal Article

Substances mentioned in the article: Plant Extracts; Receptors, Adrenergic; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, Dopamine; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Receptors, Opioid;

Mesh terms: Cell Membrane/drug effects; Humans; Plant Extracts/pharmacology; Plants, Medicinal; Receptors, Adrenergic/drug effects; Receptors, Cell Surface/drug effects; Receptors, Cholinergic/drug effects; Receptors, Dopamine/drug effects; Receptors, GABA-A/drug effects; Receptors, Glycine; Receptors, Neurotransmitter/drug effects; Receptors, Opioid/drug effects;

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