720385

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720385 [2018/11/22 21:16] (current)
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 +====== Influence of GABA receptor agonists and antagonists on the binding of 3H-diazepam to the benzodiazepine receptor.======
 +
 +** Article date:** 1978/11/1
 +~~META:date created = 1978-11-01~~
 +
 +** PubMed ID: 720385 **
 +
 +** Journal name: European journal of pharmacology (ISSN: 0014-2999) **
 +
 +** ABSTRACT **
 +
 +The GABA receptor agonists, GABA and muscimol, increased, while the GABA receptor antagonist, (+)-bicuculline,​ decreased the affinity of the benzodiazepine receptor for 3H-diazepam. The effect was seen at both 0 and 25 degrees C in spite of a large difference of affinity for 3H-diazepam at the two temperatures.
 +
 +===== ===== 
 +
 +{{gview 100%,​450px>​ http://​directlinks.cc/​files/​muscimol/​720385.pdf}}
 +
 +Author List: Briley M S, Langer S Z
 +
 +Publication Types: Journal Article
 +
 +Substances mentioned in the article: GABA Antagonists;​ Receptors, Drug; Benzodiazepines;​ Muscimol; gamma-Aminobutyric Acid; Diazepam; Bicuculline; ​
 +
 +Mesh terms: Animals; Benzodiazepines/​metabolism;​ Bicuculline/​pharmacology;​ Brain/​metabolism;​ Diazepam/​metabolism;​ GABA Antagonists;​ In Vitro Techniques; Muscimol/​pharmacology;​ Rats; Receptors, Drug/​metabolism;​ gamma-Aminobutyric Acid/​metabolism; ​
 +
 +{{tag> Bicuculline GABA_Antagonists Diazepam Receptors,​_Drug gamma-Aminobutyric_Acid Benzodiazepines Muscimol }}
 +
 +{{keywords>​ Bicuculline,​ GABA Antagonists,​ Diazepam, Receptors, Drug, gamma-Aminobutyric Acid, Benzodiazepines,​ Muscimol}}
 +
  
720385.txt · Last modified: 2018/11/22 21:16 (external edit)