Article date: 1995/4/1
PubMed ID: 7619304
Journal name: Behavioural brain research (ISSN: 0166-4328)
This study was designed to investigate the effects of different recognition procedures on memory performance in Balb/c mice. To this end, mice were submitted to spontaneous or contingently reinforced delayed non-matching (DNMTP) and delayed matching (DMTP) to place tasks in a T-maze. Results indicate that mammillary bodies (MM)-lesioned subjects are significantly impaired in the DNMTP tasks at the long (6 h) but not the short (5 min) delays; in contrast, they did not exhibit deficits in the DMTP task, whatever the delay considered. We stress the importance of task difficulty as a major factor explaining the different effects of the lesion in the two tasks.
Author List: Béracochéa D J, Jaffard R
Publication Types: Journal Article; Research Support, Non-U.S. Gov't
Substances mentioned in the article: Ibotenic Acid;
Mesh terms: Animals; Conditioning, Operant/physiology; Food; Ibotenic Acid/toxicity; Male; Mammillary Bodies/anatomy & histology; Memory/physiology; Mice; Mice, Inbred BALB C; Reinforcement (Psychology); Reward; Space Perception/physiology;