Article date: 1994/5/19
PubMed ID: 8084539
Journal name: Neuroscience letters (ISSN: 0304-3940)
Electrical and chemical lesions in the ventrolateral pons produced apneustic breathing in anesthetized, vagotomized, paralyzed, ventilated adult rats (n = 13). Apneustic breathing did not develop if the vagi remained intact and was reversed partially with vagal (proximal end) stimulation. Physiologically, these data are similar to those obtained following dorsolateral pontine lesion in rat and other mammalian species and support the hypothesis that pontine neurons influence breathing similarly across mammalian species.
Author List: Jodkowski J S, Coles S K, Dick T E
Publication Types: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
Substances mentioned in the article: Muscimol;
Mesh terms: Animals; Electric Stimulation; Male; Muscimol/pharmacology; Neurons/drug effects; Phrenic Nerve/cytology; Pons/cytology; Rats; Rats, Sprague-Dawley; Respiratory Mechanics/drug effects; Vagotomy;