Binding of [3H]GABA and [3H]muscimol to subcellular particles of a neurone-enriched culture of mouse brain.

Article date: 1980/5/15

PubMed ID: 891679

Journal name: Experientia (ISSN: 0014-4754)


Binding of [3H]GABA and [3H]muscimol, indicative of GABA-receptors, has been demonstrated in a neurone-enriched culture of embryonic mouse brain using a ligand-binding technique. Evidence is provided for the existence of different populations of GABA-receptors.

Author List: Sarliève L L, DeFeudis F V, Ossola L, Mandel P

Publication Types: Journal Article

Substances mentioned in the article: Ligands; Oxazoles; Receptors, Drug; Tritium; Muscimol; gamma-Aminobutyric Acid;

Mesh terms: Animals; Binding, Competitive; Brain/metabolism; Cells, Cultured; Embryo, Mammalian; Kinetics; Ligands; Mice; Muscimol/metabolism; Neurons/metabolism; Oxazoles/metabolism; Protein Binding; Receptors, Drug/metabolism; Tritium; gamma-Aminobutyric Acid/metabolism;

Citations: - Muscimol binding in rat brain: association with synaptic GABA receptors.

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